Whenever WebSphere Application Server settings are changed in the Deployment Manager, these changes are not pushed down to all nodes automatically by default.  Therefore a manual synchronization must be triggered to get these changes pushed to all cluster members.  This can be automated by doing the following steps:

In the Integrated Solution Console (ICS) open System administration on the left hand menu and the click on  Console Preferences.

Now you can set the checkmark on the right side at Synchronize changes with Nodes.

Once you click on “Apply” all changes in the ICS will be pushed down to all available cluster members whenever “save” is clicked.